Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.310 AlteredExpression disease BEFREE Thus, we provide the first evidence of FosB gene expression in human HPC and PFC in these psychiatric disorders, and in light of recent findings demonstrating the critical role of HPC ΔFosB in rodent models of learning and memory, these data suggest that reduced ΔFosB in HPC could potentially underlie cognitive deficits accompanying chronic cocaine abuse or depression. 27494187 2016
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.310 Therapeutic disease CTD_human Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex. 18539927 2009
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.310 Therapeutic disease CTD_human Overexpression of DeltaFosB is associated with attenuated cocaine-induced suppression of saccharin intake in mice. 19331462 2009
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.310 Biomarker disease CTD_human Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex. 18539927 2009
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.310 Biomarker disease CTD_human Overexpression of DeltaFosB is associated with attenuated cocaine-induced suppression of saccharin intake in mice. 19331462 2009
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.310 Therapeutic disease CTD_human DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction. 17898221 2007
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.310 Biomarker disease CTD_human DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction. 17898221 2007
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.310 Therapeutic disease CTD_human Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine. 12657709 2003
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.310 Biomarker disease CTD_human Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine. 12657709 2003