FPR1, formyl peptide receptor 1, 2357

N. diseases: 93; N. variants: 10
Disease: cervical cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4048328
Disease: cervical cancer
cervical cancer 		0.030 AlteredExpression disease BEFREE In this study, we developed a novel immunotherapeutic peptide by linking the <i>Mycobacterium tuberculosis</i> (MTB) heat shock protein 70 (Hsp70) functional peptide to the extracellular domain of FPR1, a protein overexpressed in cervical cancer, to obtain an MTBHsp70-exFPR1 fusion protein. 31772669 2019
CUI: C4048328
Disease: cervical cancer
cervical cancer 		0.030 Biomarker disease BEFREE The excellent capability of MtHSP70-FPR1 fusion protein to induce phenotypical and functional maturation of moDCs and CC-specific CTL responses partly illustrates the potential clinical benefits of DC-based immunotherapy for CC. 30098789 2018
CUI: C4048328
Disease: cervical cancer
cervical cancer 		0.030 Biomarker disease BEFREE FPR1 activation induced NF-κB nuclear translocation to promote cervical cancer development through the upregulation of IL-6 and IL-8 expression. 30510453 2018