The tracer thus obtained was tested in a mouse model of atherosclerosis (ApoE KO) and compared with the widely used [<sup>18</sup>F]fluorodeoxyglucose ([<sup>18</sup>F]FDG) PET tracer, known to label metabolically active cells.
In this article, we review the existing literature on the application of <sup>18</sup>F-FDG and <sup>18</sup>F-NaF as PET probes in atherosclerosis and present the findings of original animal and human studies that have examined how well <sup>18</sup>F-NaF uptake correlates with vascular calcification and cardiovascular risk.
Is <sup>18</sup>F-FDG PET/CT a valuable diagnostic tool for verifying accelerated atherosclerosis secondary to diabetes mellitus on insulin in the aortic segments and large arteries?
Uptake of the positron emission tomography (PET) tracer 2-deoxy-2-[<sup>18</sup>F]-fluoro-d- glucose ([<sup>18</sup>F]FDG) into macrophages is a sensitive marker of inflammation in atherosclerosis.