DDX58, DExD/H-box helicase 58, 23586

N. diseases: 144; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019163
Disease: Hepatitis B
Hepatitis B
0.030 Biomarker disease BEFREE The exclusive signaling specificity conferred by nuclear RIG-I is reinforced by its inability to sense cytoplasmic-replicating Sendai virus and appreciable sensing of hepatitis B virus pregenomic RNA in the nucleus. 30097581 2018
CUI: C0019163
Disease: Hepatitis B
Hepatitis B
0.030 Biomarker disease BEFREE The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus. 25557055 2015
CUI: C0019163
Disease: Hepatitis B
Hepatitis B
0.030 GeneticVariation disease BEFREE To further investigate the function of RIG-I in chronic hepatitis B virus (HBV) infection, HepG2 or HepG2.2.15 (HBV-transformed) cell lines were challenged with VSV following RIG-1 transfection. 22992810 2012