DDX58, DExD/H-box helicase 58, 23586

N. diseases: 144; N. variants: 10
Disease: HIV-1 infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.030 Biomarker disease BEFREE Functional pathway analyses revealed that a close connection with miRNA-mRNA in HIV-1 infection that DEGs were involved in response to virus and immune system process, and RIG-I-like receptor signaling pathway, whose DEMs or DEGs will be novel biomarkers for prediction of clinical outcomes and therapeutic targets for HIV-1. 28222782 2017
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.030 AlteredExpression disease BEFREE Established HIV-1 infection of monocyte-derived macrophages induced the upregulation of the pattern recognition receptors MDA5 and Rig-I that serve as virus sensors; production of interferon-β, and transcription of interferon-stimulated genes including CXCL10. 27510577 2016
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.030 AlteredExpression disease BEFREE Moreover, we demonstrated that HIV-1 infection could result in a significant increase in the level of RIG-I in human MDMs. 26535695 2015