BACE1, beta-secretase 1, 23621

N. diseases: 120; N. variants: 8
Disease: MILES-CARPENTER X-LINKED MENTAL RETARDATION SYNDROME ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1839735
Disease: MILES-CARPENTER X-LINKED MENTAL RETARDATION SYNDROME
MILES-CARPENTER X-LINKED MENTAL RETARDATION SYNDROME 		0.010 Biomarker disease BEFREE The methanolic extract of Callyspongia samarensis (MCS) significantly inhibited β-secretase 1 (IC<sub>50</sub> 99.82 µg/mL) in a dose-dependent manner and demonstrated a noncompetitive type of inhibition. 30427208 2020