BACE1, beta-secretase 1, 23621

N. diseases: 120; N. variants: 8
Disease: Postoperative cognitive dysfunction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4721773
Disease: Postoperative cognitive dysfunction
Postoperative cognitive dysfunction 		0.010 GeneticVariation phenotype BEFREE The aim of the present study was to investigate the effects of β‑site amyloid precursor protein cleavage enzyme 1 (BACE1) gene silencing on isoflurane anesthesia‑induced POCD in immature rats via the phosphatidylinositol‑3‑kinase (PI3K)/protein kinase B (Akt) signaling pathway. 30221701 2018