PLA2G15, phospholipase A2 group XV, 23659

N. diseases: 170; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.090 Biomarker disease BEFREE External validation in stable CAD (c = 0.65) and ACS (c = 0.68) demonstrated comparable performance. 31623766 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.090 GeneticVariation disease BEFREE Among them, 10 628 patients (1.9%), including 6780 (1.2%) with acute coronary syndrome ( ACS ) and 3848 (0.7%) with stable coronary artery disease, were ≥90 years of age. 30791799 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.090 Biomarker disease BEFREE Multivariate analyses indicated that GLS and GRACE ACS risk scores are independent predictors of CAD in patients with NSTEMI (GLS: OR = 0.514, P < 0.001; GRACE score: OR = 0.938, P = 0.007). 30803009 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.090 Biomarker disease BEFREE Prospective cohort study of 75 stable patients with CAD and 3 differing clinical profiles (stable angina [SA]; remote myocardial infarction [MI]; repetitive acute coronary syndrome [ACS]) and 25 controls without angiographic CAD, each with 15 hs-cTnT measurements over 1 year. 31679620 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.090 Biomarker disease BEFREE Risk stratification after percutaneous coronary intervention (PCI) is mainly based on demographics and clinical presentation (stable coronary artery disease [CAD] vs. acute coronary syndromes [ACS]). 30041804 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.090 GeneticVariation disease BEFREE We measured baseline sEPCR levels in 1673 individuals with CAD (521 with acute coronary syndrome [ACS] and 1152 with stable angina pectoris [SAP]) from the AtheroGene cohort. 23136988 2012
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.090 GeneticVariation disease BEFREE The MA of rs5065 ANP gene variant associates with increased susceptibility to ACS and has unfavorable prognostic value in CAD. 22575314 2012
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.090 GeneticVariation disease LHGDN Genetic variants and haplotypes of lipoprotein associated phospholipase A2 and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study). 18983494 2009
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.090 Biomarker disease BEFREE Hierarchical classification analysis showed that for north Greek areas family history of coronary heart disease, hypercholesterolemia, hypertension, diabetes (explained variability 35%), and less significantly, dietary habits, smoking, body mass index, and physical activity status (explained variability 4%) were associated with the development of ACS, whereas for south Greek areas hypercholesterolemia, family history of coronary heart disease, diabetes, smoking, hypertension, dietary habits, physical activity (explained variability 34%), and less significantly body mass index (explained variability <1%), were associated with the development of the disease. 18388034 2008