DIANPH, diabetic nephropathy, 23771

N. diseases: 35; N. variants: 0
Disease: Hypertrophy of kidney ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0156259
Disease: Hypertrophy of kidney
Hypertrophy of kidney 		0.010 Biomarker disease BEFREE For the early DN model rats, HKC ameliorated micro-urinary albumin, body weight and serum albumin, but had no significant effects on renal function and liver enzymes; HKC improved renal shape, kidney weight and kidney hypertrophy index; HKC attenuated glomerular hypertrophy, GBM thickening and mild mesangial expansion; HKC inhibited the phosphorylation of Akt, mTOR and p70S6K, and the protein over-expression of transforming growth factor-β1 in kidneys. 29881349 2018