ALK, ALK receptor tyrosine kinase, 238

N. diseases: 519; N. variants: 41
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
0.030 GeneticVariation phenotype BEFREE <i>ALK</i> positive patients had a higher risk of developing tumor recurrence in liver (P=0.043). 31737311 2019
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
0.030 Biomarker phenotype BEFREE We report a case of recurrence of anaplastic lymphoma kinase (ALK) rearrangement-positive lung adenocarcinoma with increased cellular pleomorphism and ALK copy number in pleural effusion cytology, and retrospectively compared the recurrent tumor with the primary tumor in terms of cytological features, immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). 29637735 2018
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
0.030 Biomarker phenotype BEFREE ALK rearrangement was not a prognostic factor for tumor recurrence or overall survival. 24815447 2014