ALK, ALK receptor tyrosine kinase, 238

N. diseases: 519; N. variants: 41
Disease: Aggressive Adult Non-Hodgkin Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0677730
Disease: Aggressive Adult Non-Hodgkin Lymphoma
Aggressive Adult Non-Hodgkin Lymphoma 		0.020 Biomarker disease BEFREE Anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma (ALK+ ALCL) is an aggressive non-Hodgkin lymphoma of T/null immunophenotype that is most prevalent in children and young adults. 21326808 2011
CUI: C0677730
Disease: Aggressive Adult Non-Hodgkin Lymphoma
Aggressive Adult Non-Hodgkin Lymphoma 		0.020 GeneticVariation disease BEFREE Anaplastic large cell lymphoma (ALCL) is a subtype of aggressive non-Hodgkin's lymphoma that is characterized by expression of CD30 and the NPM/ALK chimeric protein, which is generated by t(2;5)(p23;q35). 16533741 2005