ALOX5, arachidonate 5-lipoxygenase, 240

N. diseases: 342; N. variants: 16
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma
0.010 AlteredExpression disease BEFREE The functions of leukotriene in tumor cell proliferation and tumor growth in medulloblastoma were determined through knocking down 5-lipoxygenase (a critical enzyme for leukotriene synthesis) by shRNAs, or using 5-lipoxygenase-deficient mice. 31300449 2019