ALOX15, arachidonate 15-lipoxygenase, 246

N. diseases: 205; N. variants: 5
Disease: Cerebrovascular accident ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group BEFREE These findings have important implications for the use of 12/15-LOX inhibitors in the treatment of stroke. 31562627 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group BEFREE 12/15-Lipoxygenase (12/15-LOX) contributes to the brain damage after middle cerebral artery occlusion (MCAO) in the acute phase of stroke. 29079502 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group BEFREE 12/15-lipoxygenase (12/15-LOX) is a major contributor to delayed neuronal cell death and vascular injury in experimental stroke, but a possible role in brain injury following global ischemia has to date not been investigated. 27838820 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.040 Biomarker group BEFREE This study was designed to test the hypothesis that 12/15-lipoxygenase (12/15-LOX) inhibition would reduce HT in warfarin-treated mice subjected to experimental stroke. 28057806 2017