STH, saitohin, 246744

N. diseases: 27; N. variants: 4
Disease: Presenile dementia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.020 GeneticVariation disease BEFREE A polymorphism (Q7R) in saitohin gene inside the microtubule-associated protein tau gene has also been related to dementia. 20852909 2010
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.020 GeneticVariation disease BEFREE We also observed a trend in non-Hispanic white PDD cases with the STH 'QQ' (Tau H1/H1) genotype increased (76%) compared to PD cases without dementia (61.7%) and controls (56.6%); however, this difference was not statistically significant (PDD vs. controls OR 2.1; 95% CI: 0.8-5.8, P=0.2). 12865131 2003