IL27, interleukin 27, 246778

N. diseases: 286; N. variants: 14
Disease: Bacterial Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.050 AlteredExpression group BEFREE Murine myeloid-derived suppressor cells are a source of elevated levels of interleukin-27 in early life and compromise control of bacterial infection. 30575117 2019
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.050 Biomarker group BEFREE Taken together, we highlight a role for IL-27 in modulating innate immune responses to bacterial infection. 30209294 2018
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.050 Biomarker group BEFREE The primary analysis assessed the accuracy of IL-27 to diagnose bacterial infection in immunocompromised pediatric patients, using PCT as a comparator. 30475852 2018
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.050 AlteredExpression group BEFREE The IL-27 receptor expression is up-regulated in intestinal inflammation and during bacterial infection. 22069308 2012
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.050 Biomarker group BEFREE This work is significant as it reveals new mechanisms by which IL-27 can enhance proinflammatory responses that can occur during bacterial infections. 22156348 2012