IL27, interleukin 27, 246778

N. diseases: 286; N. variants: 14
Disease: Influenza ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021400
Disease: Influenza
Influenza 		0.040 Biomarker disease BEFREE Our data show during influenza infection myeloid cell-derived IL-27 regulates the early-phase effector functions of NK cells in the bronchioalveolar and lung tissue. 30899058 2019
CUI: C0021400
Disease: Influenza
Influenza 		0.040 AlteredExpression disease BEFREE Furthermore, we found that P28 and S65 also affect the shutoff activity of PA-X derived from other influenza virus subtypes. 30894843 2019
CUI: C0021400
Disease: Influenza
Influenza 		0.040 Biomarker disease BEFREE We now report that influenza infection induced pulmonary IL-27 production in a type I IFN-α/β receptor (IFNAR) signalling-dependent manner, which sensitized mice to secondary pneumococcal infection downstream of IFNAR pathway. 24408967 2014
CUI: C0021400
Disease: Influenza
Influenza 		0.040 Biomarker disease BEFREE We have previously demonstrated that IL-27 induces potent anti-viral effects against HIV-1, HIV-2, SIV, HSV-2, KSHV and influenza viruses in macrophages. 23535375 2013