FRZB, frizzled related protein, 2487

N. diseases: 89; N. variants: 8
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.040 PosttranslationalModification disease BEFREE Independent studies showed epigenetic silencing of SFRP3 in melanoma and hepatocellular carcinoma. 27623992 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.040 Biomarker disease BEFREE FRZB expression was up-regulated in HCC bone metastasis tissue, which suggested that FRZB might play a key role in the HCC bone metastasis. 26722540 2015
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.040 PosttranslationalModification disease BEFREE Methylation of SFRP3 promoter region in HCCs increased significantly compared with control tissues. 24591760 2014
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.040 Biomarker disease BEFREE We examined the relationship between Wnt signaling and epigenetic alteration of secreted frizzled-related protein (SFRP) genes in HCC. 18592156 2008