GAST, gastrin, 2520

N. diseases: 236; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 AlteredExpression disease BEFREE The aim of the study was to estimate the value of detecting pepsinogen (PG) I, PGII, and gastrin-17 (G-17) levels in serum for chronic atrophic gastritis (CAG) screening and to determine the clinical applicability of combined measurement of serum G-17, pepsinogens (PGI, PGII) and PGI/PGII ratio (PGR) as a screening test for CAG. 31058531 2019
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 Biomarker disease BEFREE Pepsinogens, gastrin-17, and anti-H. pylori antibodies serum assays seem to be reliable non-invasive screening tools for the presence of CAG, helpful to identify individuals to refer to gastroscopy with five standard gastric biopsies in order to obtain histological confirmation of diagnosis. 31635944 2019
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 AlteredExpression disease BEFREE NGR1 treatment significantly increased the levels of gastrin (GAS) and somatostatin (SS) and reduced motilin (MTL) in the serum of CAG rats. 30757999 2019
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 AlteredExpression disease BEFREE The aim of this study was to investigate the effects of long-term PPIs use on the gastrin levels in patients with atrophic gastritis and to determine factors affecting hypergastrinemia in long-term users of PPIs. 29310112 2018
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 AlteredExpression disease BEFREE Vonoprazan more markedly increased the blood gastrin level compared with conventional PPIs in patients with milder or no atrophic gastritis. 29393198 2018
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 Biomarker disease BEFREE So far, it has been demonstrated that serum pepsinogens (PGs), and gastrin 17 (G17) are useful for screening individuals at elevated risk to develop atrophic gastritis but they are suboptimal biomarkers to screen individuals for GC. 29518896 2018
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 Biomarker disease BEFREE Systematic review with meta-analysis: diagnostic performance of the combination of pepsinogen, gastrin-17 and anti-Helicobacter pylori antibodies serum assays for the diagnosis of atrophic gastritis. 28782119 2017
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 Biomarker disease BEFREE There are three conditions that are associated with hyperplastic changes in endocrine cells preceding GEP-NETs: autoimmune chronic atrophic gastritis or multiple endocrine neoplasia type 1 (MEN1) with gastric enterochromaffin-like (ECL) cell hyperplasia; MEN1 with gastrin and somatostatin cell hyperplasia in the duodenum and glucagon cell hyperplasia in the islets of the pancreas; and inflammatory bowel disease with endocrine cell hyperplasia in the colon. 18058264 2007
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 Biomarker disease BEFREE The aim of the study is to assess the effect of eradication therapy on atrophic gastritis and analyze the gene expression for ODC, COX-2 and gastrin in gastric mucosa after succesful eradication in patients with atrophic gastritis. 12645788 2003
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 Biomarker disease BEFREE The large majority of gastric neuroendocrine tumors is made by benign, gastrin-dependent, well-differentiated ECL cell growths arising in a background of chronic atrophic gastritis (type I) or, more rarely, associated with type I multiple endocrine neoplasia (MEN I) and Zollinger-Ellison (ZE) syndromes (type II). 10738315 2000
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 AlteredExpression disease BEFREE Autoimmune atrophic gastritis patients were younger, mainly females, with a significantly higher serum gastrin level than the H. pylori-associated atrophic gastritis group (P < 0.001). 10219822 1999
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 AlteredExpression disease BEFREE In both groups, mean gastric acid output decreased and mean fasting serum gastrin levels and the prevalence of atrophic gastritis increased with age. 432534 1979
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic
0.100 Biomarker disease BEFREE The results recommend serum PG I and serum gastrin, but not parietal cell antibody, as tests for severe atrophic gastritis in relatives of patients with pernicious anemia. 456206 1979