FUS, FUS RNA binding protein, 2521

N. diseases: 301; N. variants: 39
Disease: Histiocytosis haematophagic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0876991
Disease: Histiocytosis haematophagic
Histiocytosis haematophagic 		0.010 GeneticVariation disease BEFREE The translocation t(16;21)(p11;q22) is rare, occurs with an incidence of 1%, in acute myeloid leukemia (AML), forming TLS/FUS-ERG fusion transcript, and it is known to cause the hemophagocytosis and vacuolation of leukemic cells. 20694842 2010