FUT8, fucosyltransferase 8, 2530

N. diseases: 91; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 Biomarker disease BEFREE Our results suggest that the prognostic values of FUT8 expression on DFS may be modified by the p53 status, and the expression of FUT8 protein can be a prognostic biomarker for patients with stage II and III CRC. 29975776 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 AlteredExpression disease BEFREE Overexpression of miR-198 in CRC cell lines decreased FUT8 levels as shown by immunofluorescence analysis, and inhibited cell proliferation, migration, and invasion. 25174450 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 AlteredExpression disease BEFREE The up-regulation of fucosyltransferase 8 (FUT8), the only enzyme catalyzing α1,6-fucosylation in mammals, has been observed in several malignant cancers including liver, ovarian, thyroid, and colorectal cancers. 23267084 2013