Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0858321
Disease: Plasmodium vivax infection
Plasmodium vivax infection
0.030 Biomarker disease BEFREE First, studies of Mendelian resistance to infection have revealed an essential role of DARC-expressing erythrocytes in protection against Plasmodium vivax infection, and an essential role of FUT2-expressing intestinal epithelial cells for protection against norovirus and rotavirus infections. 31121434 2019
CUI: C0858321
Disease: Plasmodium vivax infection
Plasmodium vivax infection
0.030 Biomarker disease BEFREE Plasmodium vivax infection was thought to be absent in African populations who are Duffy blood group antigen negative (Duffy-negative). 29530446 2018
CUI: C0858321
Disease: Plasmodium vivax infection
Plasmodium vivax infection
0.030 GeneticVariation disease BEFREE The variants of the Duffy Antigen/Receptor for Chemokines (DARC) gene have probably been selected by malaria parasites, particularly the FY*O allele, which is fixed in sub-Saharan Africa and confers resistance to Plasmodium vivax infection. 30218021 2018