CERS6, ceramide synthase 6, 253782

N. diseases: 58; N. variants: 7
Disease: Colitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009319
Disease: Colitis
Colitis 		0.020 AlteredExpression disease BEFREE Our study suggests that lack of CerS6 expression differentially impacts the development of colitis, depending on the model used. 29374263 2018
CUI: C0009319
Disease: Colitis
Colitis 		0.020 Biomarker disease BEFREE Adoptive transfer of CerS6-deficient splenocytes, which have significantly decreased levels of C<sub>16</sub>-ceramide, showed that CerS6-deficiency protected against the development of colitis. 29138469 2017