Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease PSYGENET Recently, microsatellite polymorphisms have been reported to be associated with four genes, GABRB3, MAOB, PAH, and SLC6A4, and their relationships have been tested to five symptom factors: hallucinations, delusions, negative symptoms, mania, and depression. 22414661 2013
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 GeneticVariation disease BEFREE The rs4906902 G allele of the GABRB3 gene was overrepresented in mTLE patients with depression; individuals homozygous for the G allele showed reduced GABRB3 mRNA expression. 22082659 2012
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease PSYGENET The rs4906902 G allele of the GABRB3 gene was overrepresented in mTLE patients with depression; individuals homozygous for the G allele showed reduced GABRB3 mRNA expression. 22082659 2012
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease PSYGENET We tested four genes [phenylalanine hydroxylase (PAH), the serotonin transporter (SLC6A4), monoamine oxidase B (MAOB), and the gamma-aminobutyric acid A receptor beta-3 subunit (GABRB3)] for their impact on five schizophrenia symptom factors: delusions, hallucinations, mania, depression, and negative symptoms. 19268543 2009
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 GeneticVariation disease BEFREE Patients carrying the GABRB3 G1+ allele showed stronger AE relating to negative affective change (for example, increased depression) than their GABRB3 G1- counterparts. 15296817 2004
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease PSYGENET Patients carrying the GABRB3 G1+ allele showed stronger AE relating to negative affective change (for example, increased depression) than their GABRB3 G1- counterparts. 15296817 2004
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 GeneticVariation disease BEFREE In conclusion, the present study indicates that in a population of PTSD patients, heterozygosity of the GABRB3 major (G1) allele confers higher levels of somatic symptoms, anxiety/insomnia, social dysfunction and depression than found in homozygosity. 11711165 2002
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease PSYGENET In conclusion, the present study indicates that in a population of PTSD patients, heterozygosity of the GABRB3 major (G1) allele confers higher levels of somatic symptoms, anxiety/insomnia, social dysfunction and depression than found in homozygosity. 11711165 2002