GAD1, glutamate decarboxylase 1, 2571

N. diseases: 245; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030319
Disease: Panic Disorder
Panic Disorder
0.040 Biomarker disease BEFREE Worry specifically predicted chronicity of GAD and anxiety sensitivity predicted chronicity of panic disorder and social anxiety disorder. 29758471 2018
CUI: C0030319
Disease: Panic Disorder
Panic Disorder
0.040 Biomarker disease BEFREE PTSD and unspecified anxiety-related disorders were associated with significant reductions in SI, whereas reductions in SAD, GAD, OCD, and panic disorder did not reach significance. 30107264 2018
CUI: C0030319
Disease: Panic Disorder
Panic Disorder
0.040 Biomarker disease BEFREE Patients with panic disorder exhibited significantly lower average GAD1 methylation than healthy controls (p<0.001), particularly at three CpG sites in the promoter as well as in intron 2. 23906988 2013
CUI: C0030319
Disease: Panic Disorder
Panic Disorder
0.040 GeneticVariation disease BEFREE Gender differences in associations of glutamate decarboxylase 1 gene (GAD1) variants with panic disorder. 22662185 2012