GAD2, glutamate decarboxylase 2, 2572

N. diseases: 173; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003467
Disease: Anxiety
Anxiety
0.080 Biomarker disease BEFREE VAs were not significantly associated with the progression of symptoms of depression (adjusted relative risk [aRR] = 1.29, 95% confidence interval [CI] = 0.94-1.77) and anxiety (aRR = 1.22, 95% CI = 0.86-1.72), or with change in average scores of PHQ-2 and GAD-2 over time, both before and after risk adjustment. 30482494 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.080 Biomarker disease BEFREE Based on the rigorous standard suggested by the Quality Assessment of Diagnostic Accuracy Studies-2, a total of 1,157 participants randomly recruited from the community completed the GAD-7, GAD-2, and other anxiety and depression measures in a counter-balanced order. 30936840 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.080 GeneticVariation disease BEFREE Parental depression and anxiety were screened with the Patient Health Questionnaire-2 (PHQ-2) and Generalized Anxiety Disorder Scale-2 (GAD-2). 31222745 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.080 GeneticVariation disease BEFREE A random sample of 688 undergraduate university students (mean age = 20.64 ±1.88 years; 53% men) completed a survey composed of a) questions about socio-demographics, academics, lifestyle behaviors, personality type, and smartphone use-related variables; b) 26-item Smartphone Addiction Inventory (SPAI) Scale; and c) brief screeners of depression and anxiety (PHQ-2 and GAD-2), which constitute the two core DSM-IV items for major depressive disorder and generalized anxiety disorder, respectively. 28777828 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.080 GeneticVariation disease BEFREE We evaluated the association of PC-related anxiety (MAX-PC) with sociodemographic characteristics, family history of PC, global health status/quality of life (EORTC QLQ-C30), depression and anxiety (PHQ-2; GAD-2), latest PSA level, time since radical prostatectomy, and current therapy. 28528448 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.080 Biomarker disease BEFREE The Generalized Anxiety Disorder Scales GAD-7 and GAD-2 are instruments for the assessment of anxiety. 28088111 2017
CUI: C0003467
Disease: Anxiety
Anxiety
0.080 Biomarker disease BEFREE FMR1 gene polymorphisms, dopaminergic (DAT, DRD, COMT), serotonin (5-HTTLPR, HTR1A, HTR2A), interleukins, MCR1, HCN (potassium channel), neurorregulinas, GABAergic (GABA, GAD, DBI) DBI, GABA (Gabra) receptors and GAD genes (GAD1, GAD2) appear to contribute to generate condition of depression or anxiety like. 25106036 2014
CUI: C0003467
Disease: Anxiety
Anxiety
0.080 GeneticVariation disease BEFREE These results support earlier studies that suggest associations of polymorphisms within the GAD2 locus with anxiety and affective disorders. 19229853 2009