KLK5, kallikrein related peptidase 5, 25818

N. diseases: 59; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.060 AlteredExpression disease BEFREE Quantitative assessment and clinical relevance of kallikrein-related peptidase 5 mRNA expression in advanced high-grade serous ovarian cancer. 31307411 2019
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.060 AlteredExpression disease BEFREE Immunofluorometric quantification of human kallikrein 5 expression in ovarian cancer cytosols and its association with unfavorable patient prognosis. 15004490 2004
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.060 AlteredExpression disease LHGDN We also found that one novel KLK5 transcript with a short 5'-untranslated region and a novel KLK7 transcript with a long 3'-untranslated region were highly expressed in the ovarian cancer cell lines OVCAR-3 and PEO1, respectively, but were expressed at very low levels in normal ovarian epithelial cells. 12738725 2003
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.060 AlteredExpression disease BEFREE KLK5 was shown to be differentially expressed at the mRNA level in breast and ovarian cancer. 12873991 2003
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.060 Biomarker disease LHGDN The human kallikrein protein 5 (hK5) is enzymatically active, glycosylated and forms complexes with two protease inhibitors in ovarian cancer fluids. 12890555 2003
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.060 Biomarker disease BEFREE We have thus hypothesized that KLK5 may be a new prognostic indicator in ovarian cancer. 11237385 2001