NOCT, nocturnin, 25819

N. diseases: 28; N. variants: 4
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.030 AlteredExpression disease BEFREE Therefore, posttranscriptional control by Nocturnin regulates the amplitude of these critical metabolic pathways, and loss of this activity results in increased metabolic flux and reduced obesity. 29386110 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE Mice lacking the Noc gene display resistance to diet-induced obesity and hepatic steatosis, due in part to reduced lipid trafficking in the small intestine. 22608110 2012
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE Importantly, mice deficient in nocturnin are protected from diet-induced obesity, exhibit impaired circadian expression of PPARγ and have increased bone mass. 20820194 2010