GALR1, galanin receptor 1, 2587

N. diseases: 44; N. variants: 4
Disease: Neuralgia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.020 Biomarker phenotype BEFREE Our previous research has shown that the expression of GalR1 is upregulated and that GalR1 activation in the nucleus accumbens (NAc) of rats with neuropathic pain has an antinociceptive effect. 31085289 2019
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.020 Biomarker phenotype BEFREE These results suggested that GalR1 induced an antinociception via inhibiting PKA activation, implying that GalR agonists may be potential and potent therapeutic options to treat chronic neuropathic pain. 30904004 2019