SUMF2, sulfatase modifying factor 2, 25870

N. diseases: 59; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE Our results document the existence of two international MRSA clones: (1) the Iberian clone (ST247:SCCmec IA:PFGE A:ribotype H2), endemic in the hospital and associated to a single multiresistant phenotype; and (2) clone EMRSA-15 (ST22:SCCmec IV:PFGE H-ribotype H7), appearing in the beginning of 2002 and associated with three phenotypes. 15383165 2004
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE In this study DNA fingerprinting by PFGE was performed on fusidic acid- and rifampicin-resistant isolates from Malaysian hospitals to determine the genetic relatedness of these isolates and their relationship with the endemic MRSA strains. 12466411 2002
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE Variation in the RFLP-PFGE pattern was shown to occur following lysogenization of phage-sensitive MRSA. 8789023 1996
CUI: C0004610
Disease: Bacteremia
Bacteremia
0.050 Biomarker disease BEFREE As far as we know, this is the first study which has investigated and compared the serotypes, phylogroups, clonotypes, virotypes, and PFGE profiles of ST131 and non-ST131 clones of bacteraemia ESBL-EC isolates.Of the 2,427 <i>E. coli</i> bloodstream isolates, 96 (4.0%) were positive for ESBL production: 40 for CTX-M-15, 36 for CTX-M-14, eight for CTX-M-1, four for CTX-M-9, CTX-M-32, and SHV-12. 31379759 2019
CUI: C0004610
Disease: Bacteremia
Bacteremia
0.050 GeneticVariation disease BEFREE Those isolates causing bacteremia in two infants clustered in PFGE pattern 3. 31413826 2019
CUI: C0004610
Disease: Bacteremia
Bacteremia
0.050 Biomarker disease BEFREE For a 1-year period, all non-duplicate P. aeruginosa isolated from bacteremia and pulmonary infections in ten adult ICUs of six French university hospitals were characterized by antimicrobial susceptibility testing and genotyping (MLST and PFGE). 30826996 2019
CUI: C3266262
Disease: Multiple Chronic Conditions
Multiple Chronic Conditions
0.050 Biomarker disease BEFREE Bacterial clonal relatedness was established using REP-PCR, PFGE, and multi-locus sequence typing (MLST). 30677535 2019
CUI: C3266262
Disease: Multiple Chronic Conditions
Multiple Chronic Conditions
0.050 Biomarker disease BEFREE CRISPR-multi-locus virulence sequence typing (CRISPR-MVLST) was performed to type 92 S. Typhimurium strains isolated from humans and food sources between 1983 and 2013 in Brazil and assess the suitability of this methodology comparing it with PFGE already used for subtyping the same strains. 28034696 2017
CUI: C0004610
Disease: Bacteremia
Bacteremia
0.050 Biomarker disease BEFREE Lactobacillus bacteremia was associated with candidemia and occurred while the patient was receiving a probiotic formulation containing the same strain (as determined by PFGE typing), and was being concomitantly treated with i.v. vancomycin, to which the Lactobacillus strain was resistant. 26024568 2015
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.050 Biomarker disease BEFREE Using a series of alternative genotyping approaches [PFGE, random amplification of polymorphic DNA (RAPD), variable number of tandem repeats (VNTR) and multilocus sequence typing (MLST)], the six CF clone D isolates and eight previously identified clone D isolates associated with infections leading to keratitis were compared. 23105019 2013
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.050 Biomarker disease BEFREE P. aeruginosa isolates (313 isolates from 142 sputum samples and 53 throat swabs) from 68 CF patients were examined using PFGE to explore the diversity of P. aeruginosa isolates among CF patients in a Dublin paediatric hospital. 21921114 2012
CUI: C3266262
Disease: Multiple Chronic Conditions
Multiple Chronic Conditions
0.050 Biomarker disease BEFREE Isolates were characterized for antibiotic susceptibility, mec gene presence, PFGE, spa type, SCCmec-type, presence of PVL genes and multi-locus-sequence-type (MLST). 22916171 2012
CUI: C3266262
Disease: Multiple Chronic Conditions
Multiple Chronic Conditions
0.050 Biomarker disease BEFREE XbaI-digested PFGE patterns generated two related clusters implicated in the dissemination of multi-drug resistance amongst Salmonella Stanley isolates. 21061061 2011
CUI: C0004610
Disease: Bacteremia
Bacteremia
0.050 Biomarker disease BEFREE MLST and PFGE analyses showed that ST11 was dominant in ESBL-producing K. pneumoniae isolates causing UTI (57.4 %) and in those causing bacteraemia (70.0 %) and has been prevalent in Korean hospitals. 20360396 2010
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.050 Biomarker disease BEFREE Linked rep-PCR profiles were observed for isolates recovered from a same family of cystic fibrosis (CF) patients, for the etiological agents of clustered cases of nosocomial infections, and for some isolates recovered from a same hospital room. rep-PCR and pulsed-field gel electrophoresis SpeI restricted genomic DNA (PFGE-SpeI) profiles were compared. 19449044 2009
CUI: C3266262
Disease: Multiple Chronic Conditions
Multiple Chronic Conditions
0.050 Biomarker disease BEFREE In total, 301 non-repetitive MRSA clinical isolates, recovered from 19 Italian hospitals between 1990 and 2007 were selected and analyzed for their antibiotic resistance, typed by PFGE and SCCmec, grouped into clonal-types and further characterized using Multi Locus Sequence Typing (MLST). 19552801 2009
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.050 Biomarker disease BEFREE This study investigated the PFGE genetic pattern and antimicrobial resistance profile of 42 A. xylosoxidans isolates obtained over 4 years from the respiratory tract of 22 CF patients. 19024606 2008
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.050 Biomarker disease BEFREE Using PFGE mapping and the three jump clones, we found it possible to orient D7S8 on the chromosome and, by linkage analysis, to further narrow the CF region by 100 kb. 2565081 1989
CUI: C0013371
Disease: Shigella Infections
Shigella Infections
0.040 Biomarker group BEFREE The aim of this study was to analyze the epidemiological relatedness of Shigella strains isolated from children during one year period by PFGE method and to investigate antimicrobial resistance determinants and cassettes among Shigella species.The occurrence of Shigella spp. in the present study was 1.32% during the study period and the majority of cases (56 (80%)) were occurred during autumn while Shigella sonnei was the most prevalent species identified. 26117443 2015
CUI: C0013371
Disease: Shigella Infections
Shigella Infections
0.040 GeneticVariation group BEFREE In this study, characterization of those provisional serovars of Shigella was performed with respect to their antimicrobial resistance, plasmids, virulence genes and PFGE profiles. 25261061 2014
CUI: C0013371
Disease: Shigella Infections
Shigella Infections
0.040 Biomarker group BEFREE Shigella isolates producing extended-spectrum β-lactamases (ESBLs) or resistance to ciprofloxacin were further characterized by PFGE to determine the genetic relatedness. 21859815 2011
CUI: C0013371
Disease: Shigella Infections
Shigella Infections
0.040 Biomarker group BEFREE Six of the isolates were identical in DNA pattern by PFGE with the seventh exhibiting a closely related pattern; both patterns were distinguishable from all other Shigella and Escherichia coli patterns. 17446289 2007
Invasive Streptococcus pneumoniae disease
0.020 Biomarker disease BEFREE All tested strains demonstrated five MLVA patterns and two PFGE patterns.<b>Conclusion.</b> We determined that the 2016-2017 outbreak of IPD in Chiba Prefecture was caused by clonally related isolates of serotype 12F. 31347997 2019
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection
0.020 GeneticVariation group BEFREE Real time PCR of csgD and csgA genes of 50 E. cloacae complex in relation to PFGE and hsp60 genotypes showed that all the genetic clusters are not equally involved in pathogenesis of urinary tract infections. 27354208 2016
Invasive Streptococcus pneumoniae disease
0.020 Biomarker disease BEFREE The purpose of this study was to evaluate the bacterial genotypes (by PFGE and MLST), clinical characteristics of patients (from review of medical records) and antimicrobial susceptibility of serogroup 20 isolates which were recovered from patients with invasive pneumococcal disease (IPD) from 2007 to 2012. 27527077 2016