SUMF2, sulfatase modifying factor 2, 25870

N. diseases: 59; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0201874
Disease: Amino acids measurement
Amino acids measurement
0.100 GeneticVariation group GWASCAT Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. 30659259 2019
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 GeneticVariation disease BEFREE Based on these results, six strains of S. aureus were identified: two MRSA strains (t16708/ST3862/PFGE-A, t16709/ST3862/PFGE-C) and one methicillin-sensitive S. aureus (t8397/ST3884/PFGE-D) were characterized for the first time in this study; strains belonging to spa types t189 and t4167 have been identified in primates in previous studies. 30481118 2019
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 GeneticVariation disease BEFREE The single MRSA belonged to the EMRSA-15 clone (PFGE D, ST15-SCCmec IVh, and spa type t790). 31332610 2019
CUI: C0428210
Disease: Methionine measurement
Methionine measurement
0.100 GeneticVariation phenotype GWASCAT Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. 30659259 2019
CUI: C0523888
Disease: Serine measurement
Serine measurement
0.100 GeneticVariation phenotype GWASCAT Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. 30659259 2019
CUI: C0523920
Disease: Threonine measurement
Threonine measurement
0.100 GeneticVariation phenotype GWASCAT Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. 30659259 2019
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE PFGE analysis revealed 22 different patterns, with four major patterns that accounted for 53.4% of all MRSA isolates, and seven sporadic patterns. 25858549 2015
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE We compared WGS to PFGE for investigating presumptive outbreaks involving three important pathogens: vancomycin-resistant Enterococcus faecium (n=19), methicillin-resistant Staphylococcus aureus (n=17), and Acinetobacter baumannii (n=15). 25631811 2015
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE The two Community-associated (CA)-MRSA belonged to ST5 but were unrelated based on the PFGE results. 24990470 2014
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE The first MRSA strain with a USA300 PFGE pattern was isolated in 2001 from a patient visiting from the USA. 25200859 2014
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE MRSA isolates belonged to three clonal complexes: CC8 (PFGE type B-ST8-t064/t451-IVg/V), CC88 (PFGE E-ST88-t186/t786-IVa), and CC5 (PFGE K-ST5-t105-IVa/PFGE K-ST105-t002-II). 24024594 2014
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE All isolates were characterized by spa typing, with selective PFGE and MLST to relate spa types with major MRSA clones. 23637976 2013
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE Two of these persons lived on farms with livestock positive for mecC-carrying MRSA, sharing spa type (t843), MLVA (MT429) and PFGE pattern with the human isolates. 23078039 2013
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE Seventeen human and animal MRSA-ST398 isolates showed indistinguishable PFGE patterns (A1-spa-t011 or B2-spa-t108) and similar phenotypic-genotypic characteristics, including the presence of the lnu(A) gene, associated with lincomycin resistance. 21682806 2011
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 GeneticVariation disease BEFREE Of the hospital-acquired MRSA cases, 14/28 (50%) were SCCmec type IV (3 PFGE types), 13 were SCCmec type III (46%), and one had an indeterminate type. 22189732 2011
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 GeneticVariation disease BEFREE Furthermore, possible transmission among veterinarians and their family members was investigated and an outbreak of ST398 MRSA in a residential care facility was confirmed with the Cfr9I PFGE. 20144202 2010
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE The epidemiology of MRSA has been investigated by PFGE. 19588195 2009
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE Methicillin-resistant Staphylococcus aureus (MRSA) PFGE strain type USA300 (multilocus sequence type 8, clonal complex 8, staphylococcal cassette chromosome mec type IV) was first reported in the USA as a cause of skin and soft issue infection among college football players in Pennsylvania and among prisoners in Missouri in 2000. 19608582 2009
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE Antibiogram profile and PFGE were also used to characterize MRSA isolates (n = 601). 18755697 2008
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 GeneticVariation disease BEFREE Slight variations in the SmaI-PFGE pattern of the clinical MRSA isolates belonging to this clone were traced back to differences in the sizes of the SCCmec J2 regions and/or to a 6.4-kb deletion extending from ISS* to the right end ISS. 17605795 2007
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 GeneticVariation disease BEFREE PFGE demonstrated that 39 (34%) of the 116 isolates were the MRSA USA300 genotype; 34 (29%) were USA100; 42 (36%) were USA500; and 1 (1%) was USA800. 16447110 2006
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE The combined use of spa and PFGE typing allowed better discrimination than each method used individually, and provided useful information on MRSA transmission between animal and human individuals. 17030517 2006
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE In addition, PFGE was performed to type the MRSA and grouped the tested 30 MRSA isolates with qacA/B into 21 PFGE types. 15888465 2005
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE PFGE analysis revealed that most MRSA isolates were indistinguishable (56%) or closely related (26%) to EMRSA-15, one of the two epidemic MRSA strains dominant in UK hospitals. 16141276 2005
MRSA - Methicillin resistant Staphylococcus aureus infection
0.100 Biomarker disease BEFREE Our data suggest that a typing method based on RAPD combined with HVR-PCR may be useful to compare MRSA isolated in a hospital environment, whereas PFGE may be used for further analysis. 15782627 2005