SH2B1, SH2B adaptor protein 1, 25970

N. diseases: 62; N. variants: 6
Disease: Alzheimer's Disease ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.020 Biomarker disease BEFREE The present study aimed to investigate the neuroprotective effects of PSM-04 on AD and reveal the possible molecular mechanism. 30733674 2019
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.020 Biomarker disease BEFREE Thus, SH2B1 may be an upstream modulator of Aβ metabolism, acting to inhibit Aβ accumulation, and has a role in the pathogenesis of AD. 27802221 2017