SH2B1, SH2B adaptor protein 1, 25970

N. diseases: 62; N. variants: 6
Disease: Neoplasms ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.090 Biomarker group BEFREE SH2B1, a member of the SH2-domain containing family, have recently been shown to act as tumor activators in multiple cancers. 30202243 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.090 Biomarker group BEFREE SH2B1, a member of the SH2-domain containing family, have recently been shown to act as tumor activators in multiple cancers, including LADC. 29380446 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.090 AlteredExpression group BEFREE miR-361-3p functions as a novel tumor suppressor in NSCLC and the anti-oncogenic activity may involve its inhibition of the target gene SH2B1. 27164951 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.090 AlteredExpression group BEFREE More importantly, high SH2B1 expression was significantly associated with tumor grade, tumor size, clinical stage, lymph node metastasis, and recurrence respectively. 22901222 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.090 AlteredExpression group BEFREE High expression of PSM-E correlated with tumor grade in prostate cancer: a new alternatively spliced variant of prostate-specific membrane antigen. 17929272 2007
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.090 AlteredExpression group BEFREE The expression of PSM-D was similar in normal and primary prostate cancer but was 2-fold higher in lymph node (p < 0.005) and bone metastases (p < 0.05) compared to the primary tumors. 12949815 2003
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.090 Biomarker group BEFREE Surprisingly, we identified a tumor cell line that is resistant to the cell cycle inhibitory effects of PSM-RB. 10498874 1999
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.090 Biomarker group BEFREE PSM has many properties that may be potentially useful as a molecular target in monoclonal antibody directed strategies of tumor imaging and therapy. 9215402 1997
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.090 Biomarker group BEFREE Further research with PSM may help us to elucidate the complex process of prostatic neoplasia better. 9126242 1997