SETBP1, SET binding protein 1, 26040

N. diseases: 257; N. variants: 28
Disease: Primary Myelofibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.020 GeneticVariation disease BEFREE In clinical course, the CNL concurrently with severe bone marrow fibrosis and dysplastic features as well as X chromosomal abnormality may predict a worsening prognosis regardless of SETBP1 mutation status. 29587671 2018
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.020 GeneticVariation disease BEFREE In this study, we describe a PMF case evolved to AML with a t(12;18)(p13;q12) rearrangement showing the downregulation of the intronic miR_4319 and the overexpression of its host gene, SET binding protein (SETBP1). 22873195 2012