Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4721806
Disease: Carcinoma, Basal Cell
Carcinoma, Basal Cell 		0.110 GeneticVariation disease BEFREE We found new BCC susceptibility loci at TGM3 (rs214782[G], P = 5.5 × 10(-17), OR = 1.29) and RGS22 (rs7006527[C], P = 8.7 × 10(-13), OR = 0.77). 24403052 2014
CUI: C4721806
Disease: Carcinoma, Basal Cell
Carcinoma, Basal Cell 		0.110 GeneticVariation disease GWASDB Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma. 24403052 2014
CUI: C0007117
Disease: Basal cell carcinoma
Basal cell carcinoma 		0.100 GeneticVariation disease GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
CUI: C0206710
Disease: Basal Cell Neoplasm
Basal Cell Neoplasm 		0.100 GeneticVariation disease GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
CUI: C0751676
Disease: Basal Cell Cancer
Basal Cell Cancer 		0.100 GeneticVariation disease GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
CUI: C0007117
Disease: Basal cell carcinoma
Basal cell carcinoma 		0.100 GeneticVariation disease GWASCAT Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma. 27539887 2016
CUI: C0206710
Disease: Basal Cell Neoplasm
Basal Cell Neoplasm 		0.100 GeneticVariation disease GWASCAT Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma. 27539887 2016
CUI: C0751676
Disease: Basal Cell Cancer
Basal Cell Cancer 		0.100 GeneticVariation disease GWASCAT Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma. 27539887 2016
CUI: C0007117
Disease: Basal cell carcinoma
Basal cell carcinoma 		0.100 GeneticVariation disease GWASCAT New basal cell carcinoma susceptibility loci. 25855136 2015
CUI: C0206710
Disease: Basal Cell Neoplasm
Basal Cell Neoplasm 		0.100 GeneticVariation disease GWASCAT New basal cell carcinoma susceptibility loci. 25855136 2015
CUI: C0751676
Disease: Basal Cell Cancer
Basal Cell Cancer 		0.100 GeneticVariation disease GWASCAT New basal cell carcinoma susceptibility loci. 25855136 2015
CUI: C0007117
Disease: Basal cell carcinoma
Basal cell carcinoma 		0.100 GeneticVariation disease GWASCAT Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma. 24403052 2014
CUI: C0206710
Disease: Basal Cell Neoplasm
Basal Cell Neoplasm 		0.100 GeneticVariation disease GWASCAT Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma. 24403052 2014
CUI: C0751676
Disease: Basal Cell Cancer
Basal Cell Cancer 		0.100 GeneticVariation disease GWASCAT Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma. 24403052 2014
CUI: C0004096
Disease: Asthma
Asthma 		0.100 GeneticVariation disease GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549 2011
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.020 Biomarker phenotype BEFREE The new identified miR-1260b/RGS22 axis provides useful therapeutic methods for treatment of HCC deepening on our understanding of underlying mechanisms of HCC tumorigenesis. 29038925 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.020 Biomarker phenotype BEFREE To investigate whether miR-1260b can regulate migration and invasion of hepatocellular carcinoma (HCC) by targeting RGS22. 29038925 2018
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.020 Biomarker phenotype BEFREE Therefore, RGS22 may be an important tumor suppressor gene in tumorigenesis, a potential new diagnostic and prognostic biomarker for metastasis and may translate to therapeutic opportunities for the preventive treatment of epithelial cancer metastasis. 21533872 2011
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.020 AlteredExpression phenotype BEFREE RGS22 is over-expressed in low metastatic epithelial cancers and involved in the processes of cell migration and invasion in esophageal cancer cell lines. 21533872 2011
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.010 Biomarker disease BEFREE The new identified miR-1260b/RGS22 axis provides useful therapeutic methods for treatment of HCC deepening on our understanding of underlying mechanisms of HCC tumorigenesis. 29038925 2018
CUI: C3811653
Disease: Experimental Organism Basal Cell Carcinoma
Experimental Organism Basal Cell Carcinoma 		0.010 GeneticVariation phenotype BEFREE We found new BCC susceptibility loci at TGM3 (rs214782[G], P = 5.5 × 10(-17), OR = 1.29) and RGS22 (rs7006527[C], P = 8.7 × 10(-13), OR = 0.77). 24403052 2014
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.010 Biomarker group BEFREE Therefore, RGS22 may be an important tumor suppressor gene in tumorigenesis, a potential new diagnostic and prognostic biomarker for metastasis and may translate to therapeutic opportunities for the preventive treatment of epithelial cancer metastasis. 21533872 2011
CUI: C0008626
Disease: Congenital chromosomal disease
Congenital chromosomal disease 		0.010 Biomarker group BEFREE RGS22 is a novel testis specific gene.It is located within chromosome 8q22.2, which shows high relevance with tumor chromosomal aberrations. 21533872 2011
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.010 AlteredExpression group BEFREE RGS22 is over-expressed in low metastatic epithelial cancers and involved in the processes of cell migration and invasion in esophageal cancer cell lines. 21533872 2011
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.010 Biomarker phenotype BEFREE Therefore, RGS22 may be an important tumor suppressor gene in tumorigenesis, a potential new diagnostic and prognostic biomarker for metastasis and may translate to therapeutic opportunities for the preventive treatment of epithelial cancer metastasis. 21533872 2011