GAS1, growth arrest specific 1, 2619

N. diseases: 88; N. variants: 0
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE Growth arrest specific-1 (Gas1) is a protein that induces cell arrest and apoptosis of gliomas and a soluble form, tGas1, increases these effects acting in both autocrine and paracrine manners. 24529556 2014
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE Lentiviral transfer of an inducible transgene expressing a soluble form of Gas1 causes glioma cell arrest, apoptosis and inhibits tumor growth. 20885451 2011
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE In the present work, we present evidence demonstrating that Gas1 exerts its effects inhibiting cell growth and inducing apoptosis of glioma cells in the absence of Shh. 19460624 2009
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE We suggest that Gas1 does not act in combination with p53 in the C6 and U373 glioma cell lines, inducing apoptosis and cell cycle arrest. 17599090 2007
CUI: C0017638
Disease: Glioma
Glioma 		0.050 AlteredExpression disease BEFREE Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo. 15056455 2004