Disease: Diabetes, Autoimmune ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune 		0.350 Biomarker disease BEFREE One of the genes strongly associated with autoimmune diabetes is PTPN22. 29895027 2018
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune 		0.350 Biomarker disease CTD_human Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. 30224649 2018
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune 		0.350 Biomarker disease BEFREE Interleukin (IL)-21 and protein tyrosine phosphatase non-receptor 22 (PTPN22) regulate lymphocyte function and have been implicated in the pathogenesis of autoimmune diabetes. 23480181 2013
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune 		0.350 GeneticVariation disease BEFREE The -1123G>C variant of PTPN22 gene promoter is associated with latent autoimmune diabetes in adult Chinese Hans. 21956362 2012
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune 		0.350 Biomarker disease CTD_human Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids. 21190368 2011
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune 		0.350 Biomarker disease BEFREE PTPN22 (1p13.2), STAT4 (2q32.2), CTLA4 (2q33.2), HLA (6p21), IL2RA (10p15.1), INS (11p15.5), ERBB3 (12q13.2), SH2B3 (12q24.12), and CLEC16A (16p13.13) were convincingly associated with autoimmune diabetes in adults (P ≤ 0.002), with consistent directions of effect as reported for pediatric type 1 diabetes. 21873553 2011
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune 		0.350 GeneticVariation disease BEFREE Genotype, allele, and phenotype distributions of the PTPN22 C1858T variant revealed similar frequencies in autoimmune diabetes with high GADA titer and juvenile-onset type 1 diabetes. 18056891 2008