GAS6, growth arrest specific 6, 2621

N. diseases: 190; N. variants: 7
Disease: Multiple Sclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.030 Biomarker disease BEFREE We highlight studies that explore the function of TAM signaling in myelination, the visual cortex, neural cancers, and multiple sclerosis (MS) using Gas6<sup>-/-</sup> and TAM mutant mice models. 29514053 2018
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.030 Biomarker disease BEFREE Furthermore, the effects of Gas6 on STAT3 signaling and matrix MMP9 downregulation indicate potential glial cell repair and immunoregulatory roles for Gas6, indicating that Gas6-TAM signaling could be a potential therapeutic target in MS and other neuropathologies. 27630207 2016
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.030 Biomarker disease BEFREE In this paper, we review the biology of the Gas6/TAM system and the current evidence supporting its potential role in the pathogenesis of MS. 27801848 2016