PHGDH, phosphoglycerate dehydrogenase, 26227

N. diseases: 288; N. variants: 33
Disease: Primary malignant neoplasm of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.020 Biomarker disease BEFREE Phosphoglycerate dehydrogenase (PHGDH) is the key enzyme of <i>de novo</i> serine biosynthesis over-expressed in various types of cancer including lung cancer. 29556358 2018
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.020 Biomarker disease BEFREE Moreover, MCMs and PHGDH can be poor prognostic factors for lung cancer. 29888431 2018