GATA2, GATA binding protein 2, 2624

N. diseases: 229; N. variants: 33
Disease: Dilatation of ureter ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0521620
Disease: Dilatation of ureter
Dilatation of ureter 		0.020 GeneticVariation disease BEFREE Conditional deletion of Gata2 by a Tbx18<sup>cre</sup> driver results in hydroureter formation at birth, associated with a loss of differentiated SMCs. 30916783 2019
CUI: C0521620
Disease: Dilatation of ureter
Dilatation of ureter 		0.020 Biomarker disease BEFREE Here, we report the generation and analysis of Gata2 hypomorphic mutant (Gata2(fGN)/(/fGN)) mice, which suffered from hydronephrosis and megaureter, as do the YAC-rescued Gata2 null mutants. 18233958 2008