GATA4, GATA binding protein 4, 2626

N. diseases: 336; N. variants: 72
Disease: Hepatoblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.040 AlteredExpression disease BEFREE We found that GATA4 expression was high in most hepatoblastomas but weak or negligible in normal hepatocytes. 30074440 2018
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.040 Biomarker disease BEFREE In this study, we assessed the role of GATA4 in doxorubicin-induced apoptosis of hepatoblastoma cells. 28349834 2017
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.040 AlteredExpression disease BEFREE GATA4 expression was high in Huh6 cells, and its knockdown decreased expression of Dickkopf-related protein 3 (DKK3), a gene that may contribute to premature or undifferentiated phenotypes in HB. 27788486 2016
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.040 Biomarker disease BEFREE To further investigate the role of GATA-4 in pediatric liver tumors, we used adenoviral transfections of wild-type or dominant negative GATA-4 constructs in the human HB cell line, HUH6. 21788913 2012