GATA6, GATA binding protein 6, 2627

N. diseases: 259; N. variants: 21
Disease: Adenocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.050 AlteredExpression group BEFREE Positive correlations were observed between the expression of LGR5 and cytoplasmic GATA6 in adenoma (P=0.0005; r<sub>s</sub>=0.48) and adenocarcinoma samples (P=0.007; r<sub>s</sub>=0.38): However, no significant association was observed in normal mucosa (P=0.399). 29434936 2018
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.050 Biomarker group BEFREE Squamous cell carcinomas showed frequent genomic amplifications of CCND1 and SOX2 and/or TP63, whereas ERBB2, VEGFA and GATA4 and GATA6 were more commonly amplified in adenocarcinomas. 28052061 2017
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.050 AlteredExpression group BEFREE We studied GATA6, a TF gene that is frequently amplified or overexpressed in gastric, esophageal and pancreatic adenocarcinomas. 24317510 2014
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.050 Biomarker group BEFREE A gene network centered on hepatic nuclear factor and GATA6 was identified in AC, suggesting a role in glandular cell differentiation of the cervix. 21407225 2011
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.050 Biomarker group BEFREE PCR analysis of genes selected based on DNA array experiments revealed that estimation of the ratios of GATA6 to SPRR3 allows discrimination among normal esophageal epithelium, Barrett's dysplasia, and adenocarcinoma. 15833844 2005