GATA6, GATA binding protein 6, 2627

N. diseases: 259; N. variants: 21
Disease: ovarian neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.040 GeneticVariation disease BEFREE Up to now, overexpression of the GATA6 gene has been shown to play an important role in several cancers, including lung cancer, digestive system tumors, breast cancer, and ovarian cancer. 31437305 2020
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.040 Biomarker disease BEFREE In all, GATA6 may present as a novel marker for poor prognosis in OC. 30633927 2019
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.040 Biomarker disease BEFREE Loss of GATA6 leads to nuclear deformation and aneuploidy in ovarian cancer. 19581290 2009
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.040 AlteredExpression disease BEFREE In particular, GATA6 is lost or excluded from the nucleus in 85% of ovarian tumors and GATA4 expression is absent in majority of ovarian cancer cell lines. 16607277 2006