GBA, glucosylceramidase beta, 2629

N. diseases: 319; N. variants: 157
Disease: Depressive disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.130 GeneticVariation disease BEFREE PD carriers of GBA variants are at high risk for cognitive decline and depression. 31292011 2020
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.130 GeneticVariation disease BEFREE GBA mutations are associated with a distinct profile of cognitive impairment and a greater prevalence of depression. 28802919 2017
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.130 GeneticVariation disease BEFREE Stepwise logistic regression model found that female sex, UPDRS part II score, motor fluctuation, GBA L1444P and SNCA Rep-1 variants collectively best predict depression in PD. 27745782 2016
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.130 Biomarker disease HPO