FGF21, fibroblast growth factor 21, 26291

N. diseases: 236; N. variants: 2
Disease: Lipodystrophy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023787
Disease: Lipodystrophy
Lipodystrophy 		0.030 AlteredExpression disease BEFREE We hypothesized that muscle FGF-21 mRNA would be altered in HIV patients with lipodystrophy. 23533568 2013
CUI: C0023787
Disease: Lipodystrophy
Lipodystrophy 		0.030 AlteredExpression disease BEFREE Serum FGF19 and FGF21 levels were determined in 4 groups of individuals as follows: (1) HIV-1-infected HAART patients with lipodystrophy (n = 38); or (2) without lipodystrophy (n = 34); (3) untreated (naive) HIV-1-infected patients (n = 34); and (4) healthy controls (n = 31). 23187887 2012
CUI: C0023787
Disease: Lipodystrophy
Lipodystrophy 		0.030 Biomarker disease BEFREE To delineate if adipose tissue is the predominant organ responsible for anti-diabetic effects of FGF21, we treated mice with reduced body fat (lipodystrophy mice with adipose specific expression of active sterol regulatory element binding protein 1c; Tg) with recombinant murine FGF21 (rmuFGF21). 22792234 2012