FGF21, fibroblast growth factor 21, 26291

N. diseases: 236; N. variants: 2
Disease: Liver neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.020 AlteredExpression group BEFREE Finally, mTORC1 signaling correlated with FGF21 expression in human liver tumors, suggesting that treatment of glutamine-addicted cancers with mTOR inhibitors might have beneficial effects at both the tumor and whole-body level. 25082895 2014
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.020 Biomarker group BEFREE We found that metformin increased the expression and release of FGF21 in a diverse set of cell types, including rat hepatoma FaO, primary mouse hepatocytes, and mouse embryonic fibroblasts (MEFs). 24041694 2013