FGF21, fibroblast growth factor 21, 26291

N. diseases: 236; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1397307
Disease: Cardiac fibrosis
Cardiac fibrosis
0.020 Biomarker disease BEFREE In vitro and in vivo studies further showed that FGF21 exerted a marked protective effect against cardiac fibrosis. 30582148 2019
CUI: C1397307
Disease: Cardiac fibrosis
Cardiac fibrosis
0.020 Biomarker disease BEFREE The present study aimed to further investigate the pathogenic role of FGF21 in DCM, hypothesizing that a lack of FGF21 may promote the progression of DCM by regulating the lipid metabolism, cardiac hypertrophy and cardiac fibrosis, thus deteriorating the cardiac dysfunction. 29375676 2018