GCG, glucagon, 2641

N. diseases: 441; N. variants: 10
Disease: Vomiting ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042963
Disease: Vomiting
Vomiting 		0.030 Biomarker phenotype BEFREE The risk of nausea was dose-dependent for long-acting (P = .0063) and across all GLP-1 RAs (P = .0017), and a similar trend was observed for vomiting (P = .23). 27860132 2017
CUI: C0042963
Disease: Vomiting
Vomiting 		0.030 Biomarker phenotype BEFREE In conclusion, blocking GLP-1 receptors in the brain reduces cisplatin-induced acute but not delayed emesis. 29228720 2017
CUI: C0042963
Disease: Vomiting
Vomiting 		0.030 Biomarker phenotype BEFREE GLP-1 receptors are distributed widely in the brain, where they contribute to mechanisms of emesis, reduced appetite and aversion, but it is not known if these centrally located receptors also contribute to a modulation of gastric slow wave activity, which is linked causally to nausea. 28456436 2017