GCG, glucagon, 2641

N. diseases: 441; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.030 Biomarker phenotype BEFREE The putative role of thiazolidinediones in depression has been already supported, but no clear evidence exists yet for GLP-1 functional agonists. 31153593 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.030 Biomarker phenotype BEFREE GLP-1 and GLP-1R were assayed also in the hippocampus and frontal cortex - brain regions mainly affected in depression. 30831439 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.030 Biomarker phenotype BEFREE In order to utilize GLP-2 as a clinical treatment tool for depression, we herein focused on the intranasal delivery that is non-invasive approach, because the i.c.v. administration is invasive and impractical. 27894924 2017