GCKR, glucokinase regulator, 2646

N. diseases: 136; N. variants: 23
Disease: Hyperuricemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0740394
Disease: Hyperuricemia
Hyperuricemia 		0.020 Biomarker disease BEFREE There was no evidence for an interaction of A1CF or GCKR with alcohol exposure in determining HU. 28679452 2017
CUI: C0740394
Disease: Hyperuricemia
Hyperuricemia 		0.020 GeneticVariation disease BEFREE The importance of GCKR in this protective mechanism is supported by "less-active" GCKR variants in association not only with hepatic steatosis and hyperuricaemia but also with lower fasting plasma glucose and decreased insulin resistance. 23022226 2013