NPAS4, neuronal PAS domain protein 4, 266743

N. diseases: 36; N. variants: 2
Disease: Memory impairment ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233794
Disease: Memory impairment
Memory impairment 		0.020 AlteredExpression phenotype BEFREE In addition, the inhibition of microRNA-142 following exposure to single prolonged stress exhibited decreased anxiety-like behaviors and memory deficits, as well as increased expression of Npas4 and BDNF. 30857769 2019
CUI: C0233794
Disease: Memory impairment
Memory impairment 		0.020 Biomarker phenotype BEFREE These all findings suggest that hippocampal NPAS4 plays a key role in the beneficial effects of EE on the pain sensitivity, depression-like phenotype, and memory deficit in mice with neuropathic pain. 30798405 2019